Ow. Ow. Ow. Your blisters demand swift attention.

As much your blister may hurt, resist the urge to pierce it, says Rock Positano, a foot specialist at the Hospital for Special Surgery in New York City, because it will increase the risk of infection. To speed healing, wash your feet in mild soap and water, then cover the blister with a bandage. If the blister breaks on its own, cleanse the area with an iodine solution, dab on Neosporin, and cover it up again. Next time, place a soft, gel-like blister guard (such as Band-Aid Blister Block) or a blob of Chapstick on the part of your foot where the shoes rub to prevent blisters.